"Comparison of six frailty instruments in adults with heart failure: a " by Julee McDonagh, Caleb Ferguson et al. uow.edu.au - get the latest breaking news, showbiz & celebrity photos, sport news & rumours, viral videos and top stories from uow.edu.au Daily Mail and Mail on Sunday newspapers.
PLOS ONE is holding a Call For Papers on Aging in Health and Disease to highlight the latest research in this field. We interviewed Professor Edison Vidal, PLOS ONE Geriatrics and Gerontology Section Editor, to learn about his research in Geriatric Medicine, and to gain his perspective on the societal impact of aging research.
Objectives: The objectives of this study were to determine the prevalence of frailty in the context of atrial fibrillation (AF); to identify the most commonly used frailty instruments in AF; and to describe the effect of frailty on non-vitamin K oral anticoagulant (NOAC) prescription for stroke prevention in adults with AF. Methods: A systematic search of databases, including Medline, Embase, Web of Science, Cochrane Library, Scopus, and CINAHL, was conducted using search terms including “atrial fibrillation,” “frailty,” and “anticoagulation.” A narrative synthesis was undertaken. Results: A total of 92 articles were screened, and 12 articles were included. The mean age of the participants (n = 212,111) was 82 years (range = 77–85 years) with 56% of participants identified as frail and 44% identified non-frail. A total of five different frailty instruments were identified: the Frailty Phenotype (FP; n = 5, 42%), the Clinical Frailty Scale (CFS; n = 4, 33%), Cumulative Def