Unlike most major diseases, the mortality rate for liver cirrhosis continues to increase and is four times higher than 40 years ago.
The Cirrhosis Using Standard tests (Cirrus) algorithm was used to analyse anonymised NHS data from blood tests from 600,000 patients.
It picked up 70% of people with cirrhosis potentially months or years before they would have a medical emergency with liver disease, and the accuracy rate of the test was about 90%.
Professor Nick Sheron, of the Foundation for Liver Research, who started the study published in the journal BMJ Open, said early diagnosis could prompt a change in lifestyle and prevent serious disease.
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New research has shown that results of blood tests routinely performed by GPs everywhere contain a hidden fingerprint that can identify people silently developing potentially fatal liver cirrhosis.
The researchers have developed an algorithm to detect this fingerprint that could be freely installed on any clinical computer, making this a low-cost way for GPs to carry out large scale screening using patient data they already hold.
Liver cirrhosis is the second leading disease causing premature death in working-age people (after heart disease). It develops silently and most patients will have no signs or symptoms until they experience a serious medical emergency and the first admission is fatal in one in three patients. Unlike most major diseases, the mortality rate for liver cirrhosis continues to increase and is now four times higher than forty years ago.