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Early in the pandemic, researchers began exploring various avenues to repurposing drugs for COVID-19.
There are many paths to repurposing, including high-throughput drug screening, which uses automated methods to screen thousands or even millions of molecules for targeted biological activity in a disease of interest. Other approaches include focusing on a certain biological mechanism of action (like testing other antivirals in COVID); combing through clinical trial data and public records; or, in the case of sildenafil citrate (Viagra), incidental clinical observation. (See
MedPage Today s full story on how drug repurposing is gaining momentum as demand for a COVID pill grows.)
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