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 E-Mail PITTSBURGH, Feb. 22, 2021 - Compared with women whose blood pressure during pregnancy was normal, women with a history of hypertensive disorders of pregnancy, such as preeclampsia and gestational hypertension, have major differences in the structure and function of the heart a decade after childbirth, University of Pittsburgh School of Medicine researchers report today in the Journal of the American College of Cardiology. The changes, which mainly affect the left ventricle of the heart, may predispose some women to ischemic heart disease and heart failure later in life without them knowing it. The findings may help clinicians identify those at high risk of long-term cardiac complications and enable early therapeutic interventions to prevent heart disease from developing.

Kathrynl berlacherMalamo countourisFlordelizas villanuevaJanetm catovSheila davisNational institutes of health heartPitt department of medicineUniversity of pittsburgh school medicineUniversity of torontoJournal of the american college cardiologyVascular institute fellow research grantMagee womens research instituteBlood institutePittsburgh schoolAmerican collegeWomens hospital postpartum hypertension