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IMAGE: These images show how regulatory T cells (Treg cells) boost the ability of microglia cells to promote the regeneration of the brain s white matter (right), compared to a sample not. view more
Credit: Xiaoming Hu/University of Pittsburgh
PITTSBURGH, May 19, 2021 - Specialized immune cells that accumulate in the brain in the days and weeks after a stroke promote neural functions in mice, pointing to a potential immunotherapy that may boost recovery after the acute injury is over, University of Pittsburgh School of Medicine neurologists found.
The study, published today in the journal
Immunity, demonstrated that a population of specialized immune cells, called regulatory T (Treg) cells, serve as tissue repair engineers to promote functional recovery after stroke. Boosting Treg cells using an antibody complex treatment, originally designed as a therapy after transplantation and for diabetes, improved behavioral and cognitive functions for weeks after a s
Novel Immunotherapy Boosts Long-Term Stroke Recovery in Mice miragenews.com - get the latest breaking news, showbiz & celebrity photos, sport news & rumours, viral videos and top stories from miragenews.com Daily Mail and Mail on Sunday newspapers.
Yale University, United States
APS Fellow BJ Casey is internationally renowned for her groundbreaking contributions to developmental neuroscience, including the first-ever fMRI study on the healthy developing brain. Among her many accomplishments is a stunning number of incredibly successful trainees who have gone on to hold faculty positions at prestigious institutions and establish highly productive research programs.
She is known for her exceptional generosity, mentoring not only those in her own lab but many others from her institution and elsewhere, finding time for each of her mentees despite her busy schedule. Her nominators Dylan Gee of Yale and Catherine Hartley of New York University both APS Fellows and recipients of the APS Janet Taylor Spence Award for transformative early-career contributions recall working as Casey’s postdoc advisees: “Though her lab had numerous projects to which we could have contributed, BJ selflessly challenged us to develop our own ind