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FDA Approves Trastuzumab Biosimilar to Treat Forms of HER2-Overexpressing Cancer

Trastuzumab is indicated for adjuvant breast cancer, metastatic breast cancer, and gastric cancer.

Chrys kokinoFam trastuzumab deruxtecan nxkiDaiichi sankyoUs food drug administration approvalAccord biopharma incAccord biopharmaDrug administration approvalSeveral formsLocally advancedMetastatic breastPositive solid

Dr Huppert on Sequential Treatment with T-DXd and Sacituzumab Govitecan in HER2-Low Breast Cancer

Laura A. Huppert, MD, discusses the impact of sequential treatment with fam-trastuzumab deruxtecan-nxki and sacituzumab govitecan-hziy on outcomes in patients with HER2-low metastatic breast cancer, according to findings from a retrospective analysis.

San franciscoUnited statesUniversity of californiaSan francisco school of medicineSan francisco schoolT dxdSacituzumab govitecan hziyFam trastuzumab deruxtecan nxkiHer2 low metastatic breast cancer

Trastuzumab Deruxtecan May Represent Potential Option for HER2-Expressing Solid Tumors

Funda Meric-Bernstam, MD, discusses the design of the DESTINY-PanTumor02 trial, details the antitumor activity and safety of T-DXd in HER2-expressing solid tumors, and shares additional analyses that will be coming down the pike.

United statesNellieb connallyInstitute for personalized cancer therapyPhasei programDepartment of investigational cancer therapeuticsUniversity of texas md anderson cancer centerFunda meric bernstamInvestigational cancer therapeuticsPersonalized cancer therapyBreast cancerCancer centerNeoadjuvant her2Fam trastuzumab deruxtecan nxkiT dxdDestiny pantumor02 trial

Dr Meric-Bernstam on the Use of Trastuzumab Deruxtecan in HER2+ Solid Tumors

Funda Meric-Bernstam, MD, discusses the phase 2 DESTINY-PanTumor02 trial of trastuzumab deruxtecan in difficult-to-treat HER2-positive solid tumors.

United statesNellieb connallyDepartment of investigational cancer therapeuticsPhasei programUniversity of texas md anderson cancer centerInstitute for personalized cancer therapyFunda meric bernstamInvestigational cancer therapeuticsPersonalized cancer therapyBreast cancerCancer centerThe university of texas md anderson cancer centerOnclive tvHase 2 destiny pantumor02 trialFam trastuzumab deruxtecan nxki

Dr Mina on the Evolution of T-DM1 and T-DXd in HER2+ Breast Cancer

Lida A. Mina, MD, discusses the evolution of the antibody-drug conjugates fam-trastuzumab deruxtecan-nxki and ado-trastuzumab emtansine in HER2-positive breast cancer.

United statesLidaa minaDivision of hematologyMayo clinic comprehensive cancer centerWomen cancer programCancer programMayo arizona breast cancerMedical oncologyToxicity profileHer2 positive breast cancerFam trastuzumab deruxtecan nxkiAdo trastuzumab emtansineEstiny breast01Destiny breast03

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