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Metformin Shows Potential to Prevent Neovascular AMD

A case-control study of 174,000 individuals found that use of metformin was associated with a reduced odds of developing wet, age-related macular degeneration.

Dimitra skondraUniversity of chicago pritzker school medicineMerative marketscan research databasesMerative marketscan researchChicago pritzker schoolExudative age related macular degenerationXudative armd exudative amdWet amdNeovascular age related macular degenerationEovascular armdNeovascular amdEt armdWet age related macular degenerationMacular degenerationAge related macular degenerationRmd age related macular degeneration

RIBOMIC Phase I and II Data Published in the Eye: Full TOFU/RAMEN/TEMPURA Trial Results Demonstrate Clinical Proof of Concept of Umedaptanib Pegol in Exudative Age-Related Macular Degeneration (nAMD)

RIBOMIC Phase I and II Data Published in the Eye: Full TOFU/RAMEN/TEMPURA Trial Results Demonstrate Clinical Proof of Concept of Umedaptanib Pegol in Exudative Age-Related Macular Degeneration (nAMD)
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United statesUmedaptanib pegolYoshi nakamuraProduct serviceRoyal college of ophthalmologistsResults demonstrate clinical proofExudative age related macular degenerationRoyal college

High-Dose Aflibercept Sustains Outcomes Over 96 Weeks

The recently approved 8-mg dose of aflibercept has shown sustained improvement in vision and anatomical markers out to 96 weeks, according to updated clinical trial results.

Friuli venezia giuliaTel hashomerGabriel katzGenentech rochePaolo lanzettaIsraeli retina societyBoehringer ingelheimUniversity of udineRegeneron pharmaceuticalsEuropean society of retina specialistsGoldschleger eye institute at sheba medical centerDrug administrationMedscape medicalEarly treatment diabetic retinopathy studyGoldschleger eye instituteSheba medical center

Faricimab Efficacy, Safety Hold Up in Real-World Study

A real-world study of faricimab in neovascular age-related macular degeneration showed visual and anatomical improvement in line with phase 3 trials in treatment-naive and previously treated eyes.

United statesGenentech rocheAllergan abbvieDavid almeidaRegeneron pharmaceuticalsBoehringer ingelheimErie retina researchDrug administrationEyepoint pharmaceuticalsSingapore national eye centerMedscape medicalTreatment diabetic retinopathy studyExudative age related macular degenerationXudative armdRetinal diseaseMicrovascular complications of diabetes

US FDA Approves Higher Dose Regeneron Eye Disease Drug Eylea

US FDA approved a higher-dose version of Regeneron Pharmaceuticals drug Eylea for treatment of a disease that is a leading cause of blindness among the elderly, the company said in a statement.

Sandra malerJahnavi nidumoluRosalba obrienDrug administrationRegeneron pharmaceuticalRosalbao brienDiane craftExudative age related macular degenerationXudative armd exudative amdWet amdNeovascular age related macular degenerationEovascular armdNeovascular amdEt armdWet age related macular degenerationRetinal disease