Background Currently, disease control in patients with severe eosinophilic asthma is not optimistic. Competing endogenous RNA (ceRNA) networks have been found to play a key role in asthma in recent years. However, it is unclear whether ceRNA networks play an important part in severe eosinophilic asthma. Methods Firstly, gene expression profiles related to severe eosinophilic asthma were downloaded from the Gene Expression Omnibus (GEO) database. Secondly, the key modules were identified by the weighted gene co-expression network analysis (WGCNA). Thirdly, genes in modules highly associated with severe eosinophilic asthma were selected for further construction of the ceRNA network. Fourthly, Gene Ontology (GO) and Kyoto Encyclopedia of Genes and Genomes (KEGG) enrichment analyses were performed on hub genes. Finally, the results of this study were validated on the GSE143303, GSE137268, and GSE147878 datasets. Results 22 severe eosinophilic asthmatics and 13 healthy controls were extract
Let us take inspiration from those who dedicate their lives to a just world and humanity dignity for all and Dr Che Guevara’s assertion that “a true revolutionary is guided by a great feeling of love. It is impossible to think of a genuine revolutionary lacking this quality.”
The poor are systematically excluded from formal discussions in South Africa. We are usually not treated as if we are citizens, or even as human beings. It is often the norm that when grassroots organisation are actually engaged by commission of inquiries and panels our voices do not appear when the reports are released. It is as if elites just can’t hear us when we speak
The poor are systematically excluded from formal discussions in South Africa. We are usually not treated as if we are citizens, or even as human beings. It is often the norm that when grassroots organisation are actually engaged by commission of inquiries and panels our voices do not appear when the reports are released. It is as if elites just can’t hear us when we speak. The Expert Panel Report on the July unrest in KwaZulu-Natal and parts of Gauteng led by Professor Sandy Africa is an .
There’s a major brouhaha playing out ahead of the president’s State of the Nation Address and the Budget Speech later this month. It all revolves around the potential continuation of the special Covid-19 Social Relief of Distress Grant and its possible evolution to become a more widespread.