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A new study shows the isolation and sequencing of more than a century-old RNA molecules from a Tasmanian tiger specimen preserved at room temperature in a museum collection. This resulted in the reconstruction of skin and skeletal muscle transcriptomes from an extinct species for the first time. The researchers note that their findings have relevant implications for international efforts to resurrect extinct species, including both the Tasmanian tiger and the woolly mammoth, as well as for studying pandemic RNA viruses.

Marcr friedlKarolinska institutetSwedish museum of natural historyStockholm universityDepartment of molecular biosciencesGenome researchScience for life laboratoryNational bioinformatics infrastructure swedenWenner gren institute at stockholm universityWenner gren institutet at stockholm universityCentre for palaeogeneticsBeaumaris zooSwedish museumNatural historyAssociate professorMolecular biosciences