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The eLife journal has published an article titled « A Mechanistic Model for long-term Immunological outcomes in South African HIV-infected Children and Adults receiving ART », following a recent study.
Led by Eva Liliane Ujeneza, AIMS alumna and PhD researcher affiliated to AIMS and the South African Center of Excellence for Epidemiological Modelling and Analysis (SACEMA) in Cape Town,the article combines clinical data and mathematical analysis to understand how T cell numbers are affected by infection and treatment at different ages.
« The HIV global pandemic is still very much pervasive across the globe, » said Eva Liliane Ujeneza. « Even though antiretroviral treatment (ART) counter’s the virus’ highly destructive effects on the immune system’s CD4 T cells, the response to treatment varies across patients, for reasons that are not fully understood. Our study uses a combined mathematical and empirical approach, to demonstrate how age, gend