Chronic kidney disease (CKD) and skeletal disorders are highly coprevalent. Kidney osteodystrophy is present in nearly all patients with end-stage kidney diseas
27.06.2022 - – BBP-711 led to near complete inhibition of glycolate oxidase throughout the dosing period and greater than 10-fold increases in plasma glycolate, suggesting it has the potential to be both a best-in-class therapy and the first oral therapy for PH1 . Seite 1