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Vaccine types StateNews: The Pfizer and Moderna vaccines are made using messenger RNA, or mRNA, a technology that delivers a bit of genetic code to cells in effect, a recipe to make the surface protein (known as spike) on the SARS-2 virus. The proteins made with the mRNA instructions activate the immune system, teaching it to see the spike protein as foreign and develop antibodies and other immunity weapons with which to fight it. The J&J vaccine uses a different approach to instruct human cells to make the SARS-2 spike protein, which then triggers an immune response. It is what’s known as a viral vectored vaccine. A harmless adenovirus from a large family of viruses,  some of which cause common colds has been engineered to carry the genetic code for the SARS-2 spike protein. Once the adenovirus enters cells, they use that code to make spike proteins.  J&J employs this same approach to make an Ebola vaccine that has been authorized for use by the European Medicines Agency

South africaUnited statesAlex gorskyPaul stoffelsJanssen advacMathai mammenUs department of healthHuman servicesBeth israel deaconess medical centerNational institutes of healthBiomedical advanced researchNational institute of allergyWorld health organizationDevelopment authorityJanssen pharmaceutical companiesJanssen research development