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UK Research on Beige Fat Formation for Improved Glucose Metabolism Highlighted by NIDDK

Research led by Dr. Philip Kern was highlighted by the National Institute of Diabetes and Digestive and Kidney Diseases. LEXINGTON, Ky. (June 2, 2021) – Research led by University of Kentucky endocrinologist and Center for Clinical & Translational Science director Dr. Philip Kern was recently highlighted by the National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK) in its 2021 Recent Advances & Emerging Opportunities report. The publication conveys important accomplishments resulting from NIDDK-funded research, as well as the enormous promise this research holds for the future. Kern’s research demonstrated for the first time that a medication called mirabegron, already FDA-approved to treat overactive bladder, improves multiple measures of glucose metabolism in people who are overweight/obese with insulin resistance by inducing beige fat formation in their white adipose fat tissue. The findings uncover a potential new mechanism for treatment of diabetes.

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