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Aging: Clinical Trial on Reversal of Epigenetic Age

by Hannah Joy on  May 28, 2021 at 7:48 PM Can epigenetic age be reversed? Yes, says a new study by following a healthy diet and lifestyle practices. Aging published Potential reversal of epigenetic age using a diet and lifestyle intervention: a pilot randomized clinical trial which reported on a randomized controlled clinical trial conducted among 43 healthy adult males between the ages of 50-72. The 8-week treatment program included diet, sleep, exercise and relaxation guidance, and supplemental probiotics and phytonutrients. ‘Following a specific diet and lifestyle interventions may reverse Horvath DNAmAge epigenetic aging in healthy adult males.’ Genome-wide DNA methylation analysis was conducted on saliva samples using the Illumina Methylation Epic Array and DNAmAge was calculated using the online Horvath DNAmAge clock (also published in Aging).

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