A pair of gene-edited kidneys from a pig has cleared creatinine from the blood and has produced urine after xenotransplantation into a brain-dead patient.
Although urate-lowering drugs form the cornerstone of gout therapy, there are only three oral medications currently available in the United States, and all have significant limitations.
The SGLT2 inhibitor empagliflozin (Jardiance) was approved by European regulators for treating adults with chronic kidney disease. The FDA is reviewing a new drug application for this indication.