Napoli's dream season finally comes to an end on Sunday when they host Sampdoria, a last victory lap before the architect of their historic Serie A title triumph walks off into the sunset.
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Fixtures for the 2021-22 season were announced on Thursday (AEST), with the side now coached by Simone Inzaghi given a San Siro opener.
That means city rivals Milan, who were runners-up last year, will begin with an away contest against Sampdoria in the week ending August 22.
Juventus, meanwhile, will start their bid to regain the Scudetto under Massimiliano Allegri with an away fixture against Udinese.
The Old Lady host Empoli in week two before a crunch clash away to Napoli on matchday three.
A tricky start continues for Allegri as he will then face former club Milan, with Juve at home for that huge clash on matchday four.