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Promising gene therapy for FOXG1 syndrome

A viral gene therapy has reversed some brain abnormalities in infant mice with FOXG1 syndrome, a significant step toward one day treating children with this severe neurodevelopmental disorder.

South koreaSoult ukpyolsiUnited statesJae leeKathrin meyerSoo kyung leeMolecular therapy methods clinical developmentCollege of artsSamsung medical centerResearch foundationResearch centerUniversity of pennsylvaniaUb department of biological sciencesMolecular therapy methodsEmpire innovation professorEndowed professor

Groundbreaking Study Shows Promise in AAV9 Gene Therapy for FOXG1 Syndrome; Rescue of Brain Structure Abnormalities and Deficits

New publication shows groundbreaking result in FOXG1 AAV9 gene therapy studies, rescuing structural brain abnormalities caused by the pediatric rare disease,.

Kathrin meyerJae leeSoo kyung leeNicole johnsonResearch foundationMolecular therapy methods clinical development paperUniversity at buffaloMolecular therapy methods clinical developmentResearch centerChief scientific officerEmpire innovation professorEndowed professorBiological sciencesMolecular therapy methodsClinical development paper

Will Coffee Plants Survive Climate Change? Genomes Reveal Clues from the Past

Will Coffee Plants Survive Climate Change? Genomes Reveal Clues from the Past
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Noord hollandEast timorBab al mandabPatrick descombesVictor albertCarl linnaeusUb department of biological sciencesUniversity at buffaloEmpire innovation professorSpecies commonly double their genomesBrief historyGreat rift valleySoutheast asia

From Ancient Roots to Future Brews: Unveiling Coffee s Prehistoric Genome

From Ancient Roots to Future Brews: Unveiling Coffee s Prehistoric Genome
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Sri lankaGreat rift valleyEast timorVictor albertMichel rigoreauZhen wangBaba budanErwan guichouxValerie poncetSitaram rajaramanMartin smitTrevorj krabbenhoftAndrea garavitoPascal musoliMasako toma braghiniAlexandre rossi paschoal

Researchers turn to coffee genome to find key to climate-resilient coffee

While some 70% of the world’s coffee production is Arabica, the species has a low tolerance to rising temperatures and disease. Nestlé has developed a high quality Arabica reference genome – which is now a publicly available database – as part of the mission to find more climate-resilient plants.

Great rift valleyEast timorPatrick descombesBab al mandabVictor albertJeroen dijkmanInstitute of agricultural sciencesDepartment of biological sciencesUniversity at buffaloLavazza groupCollege of artsNature geneticsCoffea arabicaEmpire innovation professorBiological sciencesSoutheast asia