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Researchers uncover the physics behind formation of branching microtubules during cell division

As any cook knows, some liquids mix well with each other, but others do not. For example, when a tablespoon of vinegar is poured into water, a brief stir suffices to thoroughly combine the two liquids.

Dewdrops on a spiderweb reveal the physics behind cell structures

Loading video. VIDEO: : Researchers in the laboratories of Princeton University scientists Joshua Shaevitz, Howard Stone, and Sabine Petry have discovered that surface tension drives the liquid-like protein TPX2 to form globules that. view more  Credit: Video by the authors: Sagar U. Setru, Bernardo Gouveia, Raymundo Alfaro-Aco, Joshua W. Shaevitz, Howard A. Stone and Sabine Petry As any cook knows, some liquids mix well with each other, but others do not. For example, when a tablespoon of vinegar is poured into water, a brief stir suffices to thoroughly combine the two liquids. However, a tablespoon of oil poured into water will coalesce into droplets that no amount of stirring can dissolve. The physics that governs the mixing of liquids is not limited to mixing bowls; it also affects the behavior of things inside cells. It s been known for several years that some proteins behave like liquids, and that some liquid-like proteins don t mix together. However, very little is

Beyond ventilators: Princeton engineers design, build and program a noninvasive breathing system for COVID-19 patients

John Sullivan, Office of Engineering Communications Catherine Zandonella, Office of the Dean for Research Jan. 29, 2021 10 a.m. On April 1, 2020, as the pandemic threatened to overwhelm area hospitals, Andrew Leifer was looking for a way to help. The Princeton University physicist connected with doctors at the University of Pennsylvania Health System in Philadelphia who were working to prevent a looming shortage in machines used to keep patients breathing. Penn Medicine, which runs hospitals in Pennsylvania and New Jersey, needed specialized machines to monitor the breathing patterns and flow of oxygen to patients undergoing noninvasive ventilation, a form of respiratory support that is gentler on the lungs and has caught on in popularity during the crisis. The hospitals needed the machines to meet exacting standards, and they needed them fast. Plus, there was a catch: the parts used to build the devices were nearly impossible to find. So Leifer and his colleagues at Princeton wo

Carbon-chomping soil bacteria may pose hidden climate risk

 E-Mail IMAGE: Soil on a chip experiments conducted by Princeton researchers mimic the interactions between soils, carbon compounds and soil bacteria, producing new evidence that large carbon molecules can potentially escape the. view more  Credit: Judy Q. Yang Much of the earth s carbon is trapped in soil, and scientists have assumed that potential climate-warming compounds would safely stay there for centuries. But new research from Princeton University shows that carbon molecules can potentially escape the soil much faster than previously thought. The findings suggest a key role for some types of soil bacteria, which can produce enzymes that break down large carbon-based molecules and allow carbon dioxide to escape into the air.

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