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iStock There s good news for women of reproductive age who are coping with the debilitating side effects of uterine fibroids, the benign growths on the uterus that can cause massive bleeding, pain, anemia, painful sex, miscarriage, or infertility. A study published February 18, 2021, in the  New England Journal of Medicine has found that a daily combination oral therapy of 40 milligrams (mg) of the drug relugolix (Relugolix-CT) with small doses of synthetic estrogen (1 mg estradiol) and synthetic progesterone (.5 mg norethindrone acetate) led to dramatic improvement in symptoms and, to a lesser degree, shrinkage of the uterine fibroids themselves. The therapy, which is given as one pill, is currently under review by the U.S. Food and Drug Administration (FDA), with approval anticipated for this summer (mid-2021).

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