The Institute for Regenerative Medicine will foster research to cure a range of diseases from leukemia to Alzheimer’s disease, breast cancer, and airway diseases.
Regenerative medicine-; the process of replacing, engineering or regenerating human cells, tissues or organs-; holds exciting potential for the field of health care.
New York, New York (PRWEB) April 24, 2023 Regenerative medicine the process of replacing, engineering or regenerating human cells, tissues or organs holds
Essential Mechanisms Identified for Proper Skin Development
A severely burned left hand with permanent scars against a plain background
February 22, 2021
Share
An international research team reports that it has found that Polycomb complexes are essential for proper skin development. This latest discovery could improve development of future stem cell therapies to generate “skin on a dish” to transplant into burn victims and patients with skin-blistering disorders, according to the scientists, who published their study “Polycomb complexes redundantly maintain epidermal stem cell identity during development” in
Genes & Development.
“Polycomb repressive complex 1 (PRC1) and PRC2 are critical epigenetic developmental regulators. PRC1 and PRC2 largely overlap in their genomic binding and cooperate to establish repressive chromatin domains demarcated by H2AK119ub and H3K27me3. However, the functional contribution of each complex to gene repression has been a subject of deb