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Substantial uncertainty about clinical value of most accelerated approval cancer drugs

Substantial uncertainty about clinical value of most accelerated approval cancer drugs
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San diegoUnited statesEdwardrs cliffBydrew amorosiMindy valcarcelProgram on regulationAmerican association for cancer research annual meetingHarvard medical schoolJournal of the american medical associationAmerican associationCancer research annual meetingAmerican medical association

In 5-Year Span of FDA Accelerated Approvals in Cancer, 43% Show Confirmatory Clinical Benefit

Fifty-seven percent of drugs granted accelerated approval for a cancer indication showed clinical benefit in confirmatory studies.

San diegoUnited statesSelpercatinib retevmoEdwardrs cliffBosutinib bosulifCapmatinib tabrectaAsciminib scemblixProgram on regulationHarvard medical schoolAmerican association for cancer researchThan halfConfirmatory trials after fiveAmerican associationPublished april