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In the largest study of its kind to date, researchers at Massachusetts General Hospital (MGH), Brigham and Women’s Hospital and the Ragon Institute of MGH, MIT and Harvard have found the new mRNA COVID-19 vaccines to be highly effective in producing antibodies against the SARS-CoV-2 virus in pregnant and lactating women. The study also demonstrated the vaccines confer protective immunity to newborns through breast milk and the placenta. The study, published in the American Journal of Obstetrics and Gynecology (AJOG), looked at 131 women of reproductive age (84 pregnant, 31 lactating and 16 non-pregnant), all of whom received one of the two new mRNA vaccines: Pfizer/BioNTech or Moderna. The vaccine-induced titers or antibody levels were equivalent in all three groups. Reassuringly, side effects after vaccination were rare and comparable across the study participants. 

United statesEvan bordtAndrea edlowCaroline atyeoKathryn grayCenters for diseaseVincent centerRagon instituteEdlow labMassachusetts general hospitalAmerican journalReproductive biologyDisease controlGalit alterBrigham and women 039s hospitalCovdi 19