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In a study looking at the effects of buprenorphine in 1,200 patients with substance use disorders, the odds of precipitated withdrawal an adverse reaction caused by medications used to treat opioid dependence was less than one percent.

United statesDavid fiellinMark chungEdel aronAlberte kentKathryn hawkGail donofrioUniversity of pennsylvaniaYale school of public healthYale school of medicineUniversity of kentucky college medicineYale schoolPublic healthGaild onofrioEmergency medicineKentucky college