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Safe de-escalation of chemotherapy in HER2-positive early breast cancer

Safe de-escalation of chemotherapy in HER2-positive early breast cancer
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HER2-Directed Therapies Continue to Shape Improved Breast Cancer Outcomes

Debu Tripathy, MD, provides insights on the management of HER2-positive breast cancer, including the evolving role of trastuzumab in this population.

United statesSan antonioUniversity of texas md anderson cancer centerDepartment of breast medical oncologyDivision of cancer medicineEarly breast cancer trialist collaborative groupResearch aims to combat residual diseaseDebu tripathyAnnual miami breast cancerBreast medical oncologyCancer medicineCancer centerPositive breast cancerPartners with pertuzumabTrastuzumab withResearch aims

Neoadjuvant Chemotherapy Has Led to De-Escalation of Breast Cancer Surgery and Radiation

Terry P. Mamounas, MD, MPH, FACS, discusses treatment options after neoadjuvant chemotherapy and how neoadjuvant chemotherapy influences axillary surgery.

United statesUniversity of central floridaFlorida state universitySan antonioTerryp mamounasFlorida state university college of medicineBreast program at orlando health cancer instituteEarly breast cancer trialist collaborative groupUniversity of central florida college medicineUniversity of texas md anderson cancer centerAnnual miami breast cancerComprehensive breast programOrlando health cancer instituteCentral florida collegeFlorida state university collegeIndividualized approach

Jagsi Holds a Magnifying Glass to Radiation Oncology: Uncovering Key Disparities and When to Omit Radiation in Breast Cancer

Investigating when radiation therapy can be appropriately omitted and striving to uncover disparities are areas of focus in the field of radiation oncology.

United statesEmory universitySan antonioReshma jagsiJuliar whiteLawrencew davisEleftheriosp mamounasAmerican society for radiation oncologyEarly breast cancer trialist collaborative groupAgency for healthcare researchRadiation oncologyEmory university schoolAfrican americanOmission approachesFavorable subgroups requires carefulBurgeoning advances

Meta-Analysis Backs Nodal Radiation in Early Breast Cancer

Investigators say their meta-analysis of 16 trials spanning six decades highlights the benefits patients and oncologists can expect from regional lymph node radiation for early breast cancer.

United kingdomDavid dodwellCarolyn taylorCancer research united kingdomEarly breast cancer trialist collaborative groupResearch councilMedical researchBreast cancerAlignant breast neoplasmAlignant neoplasiaBreast conserving surgeryOnservative breast surgeryBreast preservation surgeryRadiation oncologyLymph nodesMeta analysis