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New drug combination may improve treatment for rare nerve sheath tumors

Combining a pair of experimental drugs may help treat malignant peripheral nerve sheath tumors with fewer harmful side effects, according to preliminary animal studies led by investigators at the Johns Hopkins Kimmel Cancer Center and Johns Hopkins Drug Discovery.

National institutes of healthUnited statesCzech republicJohns hopkins universityNorthwestern universityKathryn lembergBarbara slusherChristinea pratilasVerena staedtkeDianee petersNaziba nuhaJohns hopkinsLiang zhaoJoanna marieh aguilarYing wuMaryland innovation initiative award

Experimental drug combination shows promise against hard-to-treat peripheral nerve sheath tumors

Experimental drug combination shows promise against hard-to-treat peripheral nerve sheath tumors
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United statesNational institutes of healthNorthwestern universityCzech republicJohns hopkins universityJoanna marieh aguilarChristinea pratilasBarbara slusherJohns hopkinsKathryn lembergDianee petersYing wuVerena staedtkeNaziba nuhaLiang zhaoInstitute of organic chemistry

Promising Experimental Drug Combo Targets Tough Nerve Tumors

Promising Experimental Drug Combo Targets Tough Nerve Tumors
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Johns hopkins universityUnited statesNational institutes of healthCzech republicNorthwestern universityBarbara slusherJohns hopkinsJoanna marieh aguilarYing wuDianee petersLiang zhaoChristinea pratilasKathryn lembergNaziba nuhaVerena staedtkeDracen pharmaceuticals

Newfound mechanism suggests drug combination could starve pancreatic cancer

Newfound mechanism suggests drug combination could starve pancreatic cancer
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United kingdomSan diegoUnited statesBritish columbiaSeth parkerSayumi yokoyamaJoseph stecklerDiane simeoneAnita stecklerEnde zhaoDiana gonzElaine linTori rodrickAlbert sohnDouglas biancurAlec kimmelman

Drug combo safely decreases pancreatic cancer growth in mice

A new combination of treatments safely decreased growth of pancreatic cancer in mice by preventing cancer cells from scavenging for fuel, a new study finds.

San diegoUnited statesUnited kingdomBritish columbiaDiana gonzTori rodrickJoseph stecklerSayumi yokoyamaAlec kimmelmanRobert wildJoel encarnaciDouglas biancurLily ramseyAnita stecklerSeth parkerElaine lin