Dracen Announces Clinical Collaboration with Merck
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Dracen will develop sirpiglenastat (DRP-104) in combination with KEYTRUDA® in selected patients with Non-Small Cell Lung Cancer NEW YORK (PRWEB) March 08, 2021 Dracen Pharmaceuticals, Inc. (Dracen) announced today that it has entered into a clinical trial and supply agreement with Merck, known as MSD outside the United States and Canada, to evaluate the safety and efficacy of sirpiglenastat (DRP-104), Dracen’s glutamine antagonist, in combination with KEYTRUDA (pembrolizumab), Merck’s anti-PD-1 (programmed death receptor-1) therapy, in patients with solid tumors.
A Phase 1b trial will enroll locally advanced or metastatic non-small cell lung cancer (NSCLC) patients to establish the safety/tolerability of sirpiglenastat in combination with KEYTRUDA. The trial is expected to begin by first quarter 2022.