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Dual-action drug produces shows promising results in neuroendocrine tumor trial

A drug that simultaneously strikes cancer cells' growth circuits and pipeline to the bloodstream produced encouraging results in a clinical trial involving patients with advanced neuroendocrine tumors, according to a study led by Dana-Farber Cancer Institute investigators.

United statesJennifer chanJeffrey meyerhardtLily ramseyRectal cancer center at dana farberDana farber cancer instituteCancer therapy evaluation programCongress onNational clinical trials networkAlliance for clinical trials in oncologyEuropean society for medical oncologyNational cancer instituteNational institutes of healthDrug administrationProgram in carcinoidNeuroendocrine tumors

Dual-action drug produces positive results in patients with advanced neuroendocrine tumors, trial finds

Dual-action drug produces positive results in patients with advanced neuroendocrine tumors, trial finds
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United statesJennifer chanJeffrey meyerhardtNational clinical trials networkDrug administrationDana farber cancer instituteCongress onProgram in carcinoidNational cancer instituteRectal cancer center at dana farberEuropean society for medical oncologyNeuroendocrine tumorsEuropean societyMedical oncologyRectal cancer centerDouble blinded study

Dual-Action Drug Shows Promise in Neuroendocrine Tumor Trial

Dual-Action Drug Shows Promise in Neuroendocrine Tumor Trial
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United statesJennifer chanJeffrey meyerhardtNational clinical trials networkNational institutes of healthAlliance for clinical trials in oncologyNational cancer instituteEuropean society for medical oncologyDrug administrationProgram in carcinoidCongress onDana farber cancer instituteRectal cancer center at dana farberCancer therapy evaluation programNeuroendocrine tumorsEuropean society

Trial Reveals Dual-Action Drug Success in Advanced Neuroendocrine Tumors

Trial Reveals Dual-Action Drug Success in Advanced Neuroendocrine Tumors
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United statesDana farber cancer instituteJennifer chanJeffrey meyerhardtRectal cancer center at dana farberCancer therapy evaluation programCongress onProgram in carcinoidDrug administrationEuropean society for medical oncologyNational cancer instituteAlliance for clinical trials in oncologyNational institutes of healthNational clinical trials networkNeuroendocrine tumorsEuropean society

INDIGO: A Phase 3 Global, Randomized, Double-Blinded Study of Vorasidenib vs Placebo in Patients with Residual or Recurrent Grade 2 Glioma with an IDH1/2 Mutation

Timothy Cloughesy, MD, reviews data from the phase 3 INDIGO trial investigating vorasidenib in patients with residual or recurrent grade 2 glioma with an IDH1 or IDH2 mutation.

Timothy cloughesyDouble blinded studyRecurrent gradePartnership with