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Irisin-based therapies may help combat Alzheimer's disease

Researchers who previously developed the first 3D human cell culture models of Alzheimer's disease (AD) that displays two major hallmarks of the condition-;the generation of amyloid beta deposits followed by tau tangles-;have now used their model to investigate whether the exercise-induced muscle hormone irisin affects amyloid beta pathology.

Exercise Hormone Irisin May Cut Alzheimer's Brain Pathology

Exercise Hormone Irisin May Cut Alzheimer's Brain Pathology
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Exercise-induced hormone irisin may reduce Alzheimer's disease plaque and tangle pathology in the brain

Exercise-induced hormone irisin may reduce Alzheimer's disease plaque and tangle pathology in the brain
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Exercise-induced hormone irisin may reduce Al

Mass General Researchers have used a 3D human neural cell culture model to show that the exercise-induced muscle hormone, irisin, reduces the level of amyloid beta deposits associated with Alzheimer’s disease.

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