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Natural compounds in gut microbiome show promise for inflammation treatment

Researchers at the University of Toronto have found naturally occurring compounds in the gut that can be harnessed to reduce inflammation and other symptoms of digestive issues.

United statesHenry krauseJiabao liuDonnelly centreNational institutes of healthFrontiers in research fundNatural sciencesBiomolecular researchEngineering research council of canadaAmerican cancer societyUniversity of torontoNature communicationsCanadian institutes of health researchDonnelly centre for cellularTemerty facultyAgence nationale de la recherche

Researchers target neurogenesis in new approach to treat Parkinson s disease

Researchers target neurogenesis in new approach to treat Parkinson s disease
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Mandy yangDonnelly centreDonnelly centre for cellularStephane angersLeslie dan facultyTemerty facultyMedical research

U of T researchers develop new approach for controlling neuron generation in Parkinson s disease

Researchers at the University of Toronto have found a way to better control the preclinical generation of key neurons depleted in Parkinson's disease, pointing toward a new approach for a disease with no cure and few effective treatments.

Mandy yangDonnelly centreUniversity of torontoDonnelly centre for cellularStephane angersLeslie dan facultyTemerty facultyMedical researchArkinson 39s diseaseIgnaling pathwayStem cells

U of T researchers map protein network dynami

<p>An international team led by researchers at the University of Toronto has mapped the movement of proteins encoded by the yeast genome throughout its cell cycle. This is the first time that all the proteins of an organism have been tracked across the cell cycle, which required a combination of deep learning and high-throughput microscopy.</p>

Brenda andrewsAthanasios litsiosDonnelly centreNational institutes of healthCanadian institutes of health researchDonnelly centre for cellularOntario research fundBiomolecular researchCanada foundation for innovationUniversity of torontoTemerty facultyCanada foundationCanadian institutesHealth researchNational institutesOntario research

Researchers create new platform to identify proteins for targeted treatment of disease

Researchers at the University of Toronto and Sinai Health have created a new platform to identify proteins that can be co-opted to control the stability of other proteins -; a new but largely unrealized approach to the treatment of disease.

Mikko taipaleSinai healthBiomolecular researchUniversity of torontoDonnelly centreDonnelly centre for cellularLunenfeld tanenbaum research instituteTemerty facultyDrug discovery