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Researchers find how hydrocortisone improve treatment of septic shock

Sepsis is a global health problem, impacting 55 million patients and killing 11 million people each year. Sepsis treatment may include early detection, source m

United statesFrance generalÎe de franceNew south walesAnthony delaneyRomain pirracchioDjillali annaneSaclay universityGeorge institute for global healthRaymond poincareParis saclay universityGeorge instituteGlobal healthNew england journal

Association Between Administration of Systemic Corticosteroids and Mortality Among Critically Ill Patients With COVID-19: A Meta-analysis | Critical Care Medicine | JAMA

This meta-analysis pools data from 7 randomized trials to estimate the association between administration of corticosteroids vs usual care or placebo and all-ca

United kingdomFrance generalEstado do rioCity ofWestern australiaNew zealandBritish columbiaUniversity collegeNew south walesSouth australiaLas palmasUnited statesSalud carlosGran canariaIsraelita albert einsteinBristol myers squibb

Effect of Angiotensin-Converting Enzyme Inhibitor and Angiotensin Receptor Blocker Initiation on Organ Support–Free Days in Patients Hospitalized With COVID-19: A Randomized Clinical Trial | Critical Care Medicine | JAMA

This randomized clinical trial examines the effect of initiation of a renin-angiotensin system inhibitor (ACE inhibitor or an angiotensin receptor blocker) on t

Eteläuomen läiSaudi arabiaSri lankaUniversity of minnesotaUnited statesSan franciscoNew south walesCity ofUnited kingdomKrung thep mahanakhonBritish columbiaFrance generalNew zealandWestern australiaNorthern irelandSouth australia

Long-term (180-Day) Outcomes in Critically Ill Patients With COVID-19 in the REMAP-CAP Randomized Clinical Trial | Critical Care Medicine | JAMA

This secondary analysis of an ongoing adaptive platform trial examines the effect of multiple interventions for critically ill adults with COVID-19 on longer-te

United kingdomSouth australiaFrance generalCity ofBritish columbiaUnited statesWestern australiaSan franciscoNew zealand generalNew zealandEstado de pernambucoNational universityEteläuomen läiSao pauloSri lankaAr riya

Effect of Antiplatelet Therapy on Survival and Organ Support–Free Days in Critically Ill Patients With COVID-19: A Randomized Clinical Trial | Critical Care Medicine | JAMA

This randomized clinical trial assesses the effect of treatment with an antiplatelet agent vs no antiplatelet therapy on days alive and free of intensive care u

Nordrhein westfalenCity ofUnited kingdomFrance generalBritish columbiaUnited statesBedford parkSouth australiaFlinders universityWestern australiaSan franciscoNew zealand generalNew zealandEstado de pernambucoNational university of singaporeSingapore general

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