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Rheumatoid arthritis: management - The Pharmaceutical Journal

The Pharmaceutical Journal from the Royal Pharmaceutical Society

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Janssen s antibody drug shows phase 2 potential in rheumatoid arthritis

The proof-of-concept trial, dubbed IRIS-RA, is the first to investigate a treatment for rheumatoid arthritis that blocks a protein called neonatal Fc receptor (FcRn). The antibody drug nipocalimab, developed by the Janssen Pharmaceutical Companies of Johnson & Johnson, has shown early promise for treating rheumatoid arthritis (RA) in a phase 2a trial.

Peterc taylorNorman collissonUniversity of oxfordMomenta pharmaceuticalsAmerican college of rheumatologyDisease activity scoreAmerican collegeArea leadLudovic de beaucoudreyDrug adminstrationBio developmentsAntibody drug conjugatesCell amp gene therapiesOhnson amp johnsonRheumatoid arthritisPhase 2

Janssen reveals positive results for nipocalimab in rheumatoid arthritis

Janssen reveals positive results for nipocalimab in rheumatoid arthritis
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Terence rooneyDisease activity score

Rituximab Demonstrates Potential Efficacy in Treatment of Special Forms of RA

A retrospective analysis suggested that administering rituximab to patients with rheumatoid arthritis complicated by lymphoma, systemic vasculitis, or extra-articular lesions was associated with improved outcomes.

International journal of rheumatic diseasesInternational journalRheumatic diseasesClinical disease activity indexDisease activity scoreErythrocyte sedimentation rateRheumatoid arthritis

Janssen reveals positive results for nipocalimab in rheumatoid arthritis

Terence rooneyDisease activity score