Nantes aimed for an early goal and made several attempts to try and open the scoring but missed the chances that came their way.
Simon delivered a fine cross in the seventh minute of the encounter but his teammates failed to make the most of the opportunity.
Nantes then found themselves on the back foot when Ludovic Ajorque, who is eligible to play for Madagascar, broke the deadlock moments before the half-time break after he was set up by Lionel Carole.
The Canaries continued their quest for victory after the start of the second half and their efforts paid off in the 53rd minute.
Moses Simon bags assist, Castelletto scores as Nantes end winless run against Strasbourg
goal.com - get the latest breaking news, showbiz & celebrity photos, sport news & rumours, viral videos and top stories from goal.com Daily Mail and Mail on Sunday newspapers.
Estrasburgo vs PSG (1-4): París Saint-Germain sigue el paso del Lille
mediotiempo.com - get the latest breaking news, showbiz & celebrity photos, sport news & rumours, viral videos and top stories from mediotiempo.com Daily Mail and Mail on Sunday newspapers.
Mauricio Pochettino se aferra a la esperanza de que Keylor Navas no tenga nada grave
nacion.com - get the latest breaking news, showbiz & celebrity photos, sport news & rumours, viral videos and top stories from nacion.com Daily Mail and Mail on Sunday newspapers.
PSG vence y no le pierde pista al puntero francés, el Lille
expreso.ec - get the latest breaking news, showbiz & celebrity photos, sport news & rumours, viral videos and top stories from expreso.ec Daily Mail and Mail on Sunday newspapers.