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How cell identity is preserved when cells divide

How cell identity is preserved when cells divide
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Leonid mirnyDino osmanoviNational science foundationInstitute for medical engineeringNational human genome research instituteDepartment of physicsNational instituteJeremy owen phdMedical engineeringGeneral medical sciencesNational science

New insights into how cells maintain their identity over generations

Every cell in the human body contains the same genetic instructions, encoded in its DNA. However, out of about 30,000 genes, each cell expresses only those genes that it needs to become a nerve cell, immune cell, or any of the other hundreds of cell types in the body.

Leonid mirnyDino osmanoviMassachusetts institute of technologyNational human genome research instituteNational instituteInstitute for medical engineeringNational science foundationDepartment of physicsOwen phdMedical engineeringGeneral medical sciencesNational scienceDaughter cell

How cell identity is preserved when cells div

<p>A new theoretical model helps explain how epigenetic memories, encoded in chemical modifications of chromatin, are passed from generation to generation.  Within each cell’s nucleus, MIT researchers suggest, the 3D folding patterns of its genome determines which parts of the genome will be marked by these chemical modifications.</p>

United kingdomLeonid mirnyDino osmanoviNational human genome research instituteNational science foundationInstitute for medical engineeringDepartment of physicsNational instituteJeremy owen phdMedical engineeringGeneral medical sciencesNational science

3D folding of the genome: Theoretical model helps explain how cell identity is preserved when cells divide

3D folding of the genome: Theoretical model helps explain how cell identity is preserved when cells divide
phys.org - get the latest breaking news, showbiz & celebrity photos, sport news & rumours, viral videos and top stories from phys.org Daily Mail and Mail on Sunday newspapers.

Dino osmanoviLeonid mirnyInstitute for medical engineeringDepartment of physicsMedical engineering

How cell identity is preserved when cells divide

A new theoretical model helps explain how epigenetic memories, encoded in chemical modifications of chromatin, are passed from generation to generation. Within each cell’s nucleus, MIT researchers suggest, the 3D folding patterns of its genome determines which parts of the genome will be marked by these chemical modifications.

Leonid mirnyAlexander grosbergDino osmanoviNational human genome research instituteNational science foundationInstitute for medical engineeringYork universityNational instituteDepartment of physicsJeremy owen phdMedical engineeringLiving systemsNew york universityGeneral medical sciencesNational scienceEpigenetic memory