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Tirzepatide s agonist effect on GIP receptors of isolated pancreatic islet cells appears responsible for a good portion of the drug s effects beyond its GLP-1 receptor agonism.

Duke universityNorth carolinaUnited statesEli lillyNovo nordiskGerman centerDiabetes research in neuherbergDiabetes researchStructure therapeuticsDiabetes mellitus type 2Iabetes mellitus type iiType 2 diabetesIncretin hormonesBody mass index bmiEsearch in diabetesNdocrine system