Agenus Inc. (NASDAQ:NASDAQ:AGEN) Q1 2022 Earnings Conference Call May 9, 2022 08:30 ET Company Participants Christine Klaskin - Vice President of Finance, Principal Financial Officer &.
Giving Immunotherapy a Helping Hand
Source: Christoph Burgstedt/Science Photo Library/Getty Images
Giving Immunotherapy a Helping Hand
If adjusting one signal or hitting one target won’t force cancer to retreat, try adjusting multiple signals or deploying combination therapies
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Immunotherapy for cancer represents a promising alternative for many patients, but so far, it hasn’t delivered long-term benefits to a majority of patients as a standalone therapy. Fortunately, the immune system, with its complex webs of interacting networks and feedback pathways, offers myriad factors that drugs may target to summon tumor-killing resources.
Druggable factors in the tumor microenvironment are now being sought by many developers. When these factors are engaged by therapeutic molecules, it is possible to clear away immune suppressors, to boost the cytotoxicity of immune cells, or to weaken a tumor’s defenses.