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Common brain malformation traced to its genetic roots: Study

Common brain malformation traced to its genetic roots: Study ANI | Updated: Dec 29, 2020 07:38 IST Washington [US], December 29 (ANI): In new research, scientists at Washington University School of Medicine in St. Louis have shown that Chiari 1 malformation (common brain disorder) can be caused by variations in two genes involved in brain development. About one in 100 children has a common brain disorder called Chiari 1 malformation, but most of the time such children grow up normally and no one suspects a problem. But in about one in 10 of those children, the condition causes headaches, neck pain, hearing, vision and balance disturbances, or other neurological symptoms.

Common brain malformation traced to its genetic roots – Washington University School of Medicine in St Louis

David Limbrick The lowest part of a child s brain is visible below the bottom of the skull in this MRI scan and shows evidence of a Chiari 1 malformation. Researchers at Washington University School of Medicine in St. Louis have shown that Chiari 1 malformation can be caused by variations in two genes linked to brain development, and that children with large heads are at increased risk of developing the condition. About one in 100 children has a common brain disorder called Chiari 1 malformation, but most of the time such children grow up normally and no one suspects a problem. But in about one in 10 of those children, the condition causes headaches, neck pain, hearing, vision and balance disturbances, or other neurological symptoms.

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