The oral presentation includes additional results from Blue Earth's Phase 3 SPOTLIGHT study evaluating the impact of clinical factors on the detection rate of 18F-rhPSMA-7.3 PET imaging in men with suspected prostate cancer recurrence based on elevated PSA following prior therapy
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The University of Kentucky celebrates Wildcats all year long, but this Lunar New Year, there is another wild cat to celebrate. Feb. 1 marked the start of the Chinese Lunar New Year, and according to the Chinese zodiac, 2022 is the Year of the Tiger.
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IMAGE: Studying the intricacies of DNA repair mechanisms may help us understand cancer evolution better, and even provide us the weapons to fight cancer. view more
Credit: Cancer Biology & Medicine
The ongoing fight of science against cancer has made great strides, but cancer cells have not made it easy. The complexity of cancer cells and their adaptive evolutionary nature complicate the search for effective cures. Multiple DNA repair pathways in healthy cells typically work to rectify DNA damages caused by sources within the organism, like spontaneous DNA mutations, or from outside, like ultraviolet radiation.
But what happens when these pathways malfunction? It is known that deficiencies in these pathways increase the instability of the genes, and this causes cancer to develop. Therefore, detailed knowledge of how DNA repair pathways participate in this process is crucial for tracking tumor progression, understanding the emergence of drug resistance, and de