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Bernese researchers develop a second generation lung-on-chip

Bernese researchers develop a second generation lung-on-chip The lung is a complex organ whose main function is to exchange gases. It is the largest organ in the human body and plays a key role in the oxygenation of all the organs. Due to its structure, cellular composition and dynamic microenvironment, is difficult to mimic in vitro. A specialized laboratory of the ARTORG Center for Biomedical Engineering Research, University of Bern, headed by Olivier Guenat has developed a new generation of in-vitro models called organs-on-chip for over 10 years, focusing on modeling the lung and its diseases. After a first successful lung-on-chip system exhibiting essential features of the lung, the Organs-on-Chip (OOC) Technologies laboratory has now developed a purely biological next-generation lung-on-chip in collaboration with the Helmholtz Centre for Infection Research in Germany and the Thoracic Surgery and Pneumology Departments at Inselspital.

3D-printed bioresorbable airway stent

Date Time 3D-printed bioresorbable airway stent An ETH Zurich research team is using 3D printing to produce a new type of bioresorbable airway stent. This could greatly simplify the future treatment of upper airway obstruction. Narrowing of the trachea or the main bronchi due to injury or illness can end very badly. If patients get too little oxygen, they risk suffocating and often need medical help as quickly as possible. Surgeons insert stents made of medically usable silicone or metal as a way of treating these patients. Although they quickly bring relief, the implants also have disadvantages: Metal stents have to be removed surgically with some effort, which is a burden for the patients, while silicone stents often migrate away from the insertion site. The reason for this is that the implants are not adapted to a patient’s anatomy.

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