New method provides molecular insight into protein-protein interactions
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Unveiling Protein Secrets: New Insight on Molecular Interactions
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Genome-editing technique shows promise as treatment for common hereditary nerve disease
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<p>Researchers from Tokyo Medical and Dental University (TMDU) have developed a genome-editing-based technique for the treatment of Charcot–Marie–Tooth disease type 1A. In cells grown from a patient, the treatment reduced levels of the disease-causing protein – peripheral myelin protein 22 (PMP22) – and reversed many associated issues. This report provides hope for patients with Charcot–Marie–Tooth disease, which to date has no effective therapies.</p>