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Biopharmaceutical Stocks: The Next Leg Of The Rally May Begin Soon

Biopharmaceutical Stocks: The Next Leg Of The Rally May Begin Soon
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Updated MajesTEC-1 Results Continue to Show Teclistamab s Promise

Selinexor OK d for Myeloma, But Does That Make It a Good Drug?

Following is a transcript of their remarks: Vinay Prasad, MD: I m back with Aaron Goodman and Dr. Al-Ola Abdallah and we re talking about selinexor. Aaron, selinexor, good drug or great drug? How would you characterize this drug? Aaron Goodman, MD: I would characterize it as an awful drug. Prasad: Awful drug? Prasad: And why is that, sir? Goodman: Well, $2,200 to $4,000 a month, so it s clearly not cheap, yet to date there is no data that it makes the patients live longer and the toxicity profile, I would say, is not favorable. The drug company would like to remind us that it does have a novel mechanism. That s about it to me.

Pegcetacoplan Bests Eculizumab for PNH Patients

email article Results from the phase III PEGASUS trial suggest that the targeted C3 inhibitor pegcetacoplan improved hemoglobin levels better than eculizumab in patients with paroxysmal nocturnal hemoglobinuria (PNH) who were still anemic despite at least three months of eculizumab therapy. The data were presented at December s In this exclusive MedPage Today video, study co-author Ilene C. Weitz, MD, of Keck School of Medicine at the University of Southern California, discusses the trial s findings. Following is a transcript of her remarks: The PEGASUS study was a study designed to look at the effect of C3 inhibition versus C5 inhibition in patients with PNH who were already on C5 inhibition, but had a suboptimal response. Most of these patients were transfusion dependent and had hemoglobin

Early Transplant or Delayed? Multiple Myeloma Experts Debate

Following is a transcript of their remarks: Vinay Prasad, MD: All right, I m Dr. Vinay Prasad. I m an associate professor and a practicing hematologist oncologist here at the University of California San Francisco. I m joined via Zoom by two dear colleagues who are myeloma experts, Aaron Goodman, assistant professor at the University of California San Diego, an expert in bone marrow transplantation and hem malignancies, and Dr. Al-Ola Abdallah at the University of Kansas, also an expert in hematologic malignancies and bone marrow transplant. It s a pleasure to have you both here, sirs. Well, let s get started. There is so much to talk about at this year s ASH annual meeting about myeloma. All our favorite drugs are there and some of the ones we don t like too much, and so let s get started.

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