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GLP-1 Receptor Agonist Drugs Effective, Pose Complex Concerns

Drugs like Ozempic, Wegovy and Mounjaro have been around for years, but they've recently been making headlines due to a rise in popularity as weight

Research shows GLP-1 receptor agonist drugs are ef

Studies from multiple UChicago experts show that while GLP-1RA drugs are extremely effective for weight loss and Type 2 diabetes treatment, there s no one-

Research shows GLP-1 receptor agonist drugs are ef

Studies from multiple UChicago experts show that while GLP-1RA drugs are extremely effective for weight loss and Type 2 diabetes treatment, there s no one-

Comorbidity and health-related quality of life in people with a chronic medical condition in randomised clinical trials: An individual participant data meta-analysis

Author summary Why was this study done? ➢ The EuroQol-5 dimension (EQ-5D) and SF-36 are questionnaire-based tools that combine measures of physical and mental health into overall quality of life scores. These scores are used in randomised controlled trials of drug treatments to estimate how treatments affect quality of life. These estimates then inform decisions about which treatments should be offered to people with specific conditions. ➢ Multimorbidity, the presence of 2 or more conditions, makes diagnosis and treatment more complex and is associated with worse quality of life in some settings. ➢ People with multimorbidity are underrepresented in clinical trials, and little is known about whether and how multimorbidity changes quality of life in clinical trials. This makes it difficult for clinicians and clinical guideline developers to determine how results from clinical trials should be applied to people with multimorbidity. What did the researchers do and find? ➢ To

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