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Detectives: Man used fentanyl in Paducah gas station parking lot; 2 arrested

Detectives: Man used fentanyl in Paducah gas station parking lot; 2 arrested
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FDA committee favors restricting prostate cancer regimen to BRCA-positive subgroup

FDA committee favors restricting prostate cancer regimen to BRCA-positive subgroup
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United statesOlaparib lynparzaDavide mitchellJorgej nievaMindy valcarcelBymark leiserNorris comprehensive cancer centerOncologic drugs advisory committeeUniversity of colorado anschutz medical campusCancers symposiumColorado anschutz medical campusComprehensive cancer center

FDA committee favors restricting prostate cancer regimen to BRCA -positive subgroup

An FDA advisory committee recommended that a proposed indication for olaparib with abiraterone acetate as first-line treatment for metastatic castration-resistant prostate cancer be limited to patients whose tumors have BRCA mutations.The Oncologic Drugs Advisory Committee voted 11 to 1 in favor of the restriction. One committee member abstained.

United statesBymark leiserDavide mitchellMindy valcarcelOlaparib lynparzaJorgej nievaUniversity of colorado anschutz medical campusNorris comprehensive cancer centerOncologic drugs advisory committeeCancers symposiumColorado anschutz medical campusComprehensive cancer center