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Dual Bests Triple Therapy in Nonvalvular AF Patients in RE-DUAL PCI

April 09, 2021 Dropping aspirin soon after PCI seems to be the best strategy for preventing bleeding in high-risk patients with nonvalvular atrial fibrillation (AF), according to a landmark analysis of the RE-DUAL PCI trial. As reported by TCTMD, RE-DUAL PCI supported moving away from a triple-therapy strategy P2Y12 inhibitor, warfarin, and aspirin in these patients in order to lessen bleeding without increasing the risk of thrombotic events. The new data in conjunction with the rest of the available evidence, including those from AUGUSTUS, “are pretty clear that that strategy of prolonged triple therapy almost should never be used,” study co-author Deepak L. Bhatt, MD, MPH (Brigham and Women’s Hospital, Boston, MA), told TCTMD. “Our article sort of helps bring some granularity to the sort of minimum duration of aspirin that s probably needed.”

Study: Lots of Papers and Citations Don t Make for Twitter Stardom

email article Academic productivity, at least by one measure, did not factor into Twitter popularity in the interventional cardiology community, researchers found. The Hirsch index, which counts published papers and related citations, had no bearing on whether Twitter users reached the top quartile of followers (>736 followers), according to Davide Capodanno, MD, PhD, Azienda Ospedaliero-Universitaria Policlinico G. Rodolico-San Marco in Catania, Italy, and colleagues. Rather, the six independent predictors of a high total Twitter follower count were: Abundant tweets (>505 tweets): adjusted OR 16.39, 95% CI 5.90-45.57 Individual charisma ( Kardashian index >5): adjusted OR 8.66, 95% CI 2.09-35.89 Large number of accounts user follows (>309 following): adjusted OR 6.42, 95% CI 2.78-14.82

Stroke After PCI, CABG Signals Higher Long-term Mortality in Modern Era

December 08, 2020 The rate at which periprocedural stroke occurs after PCI and CABG in contemporary practice is “not negligible” and is associated with a higher long-term mortality risk, according to findings from the Japanese CREDO-Kyoto PCI/CABG registry Cohort-3. Stroke occurred within 30 days of the procedure in 0.96% of the PCI group and 2.13% of the CABG group ( P 0.001), with most of these patients leaving the hospital with at least mild disability, researchers led by Ko Yamamoto, MD (Kyoto University, Japan), report in a study published online last week in the American Journal of Cardiology. Periprocedural stroke was associated with a higher risk of mortality regardless of the mode of revascularization through a median follow-up of 5.7 years.

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