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Promising New Treatment for Patients with HR+ HER-

Promising New Treatment for Patients with HR+ HER-
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Novel KRAS G12C Inhibitor Reflects Research Advances in NSCLC and CRC

David S. Hong, MD, and David Sommerhalder, MD, discuss the unmet needs for patients with KRAS G12C–mutant non–small cell lung cancer (NSCLC) and colorectal cancer (CRC) that prompted the initiation of the RMC-6291-001 trial; the key efficacy and safety findings with RMC-6291 in patients with NSCLC and CRC; and potential next steps for this agent.

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