A transgender woman who left her aunt s partner in intensive care after punching him and a number of others in a drunken rage following a karaoke session said I m really morto with myself…why did I say yes to going to the pub after watching CCTV of the incident.
Hairdresser Shauna Kavanagh (33), who was charged under her previous name at the time of the offence, knocked out Tommy Coogan when he tried to stop the accused attacking other people outside of a Dublin pub she had been kicked out of after assaulting another man.
Mr Coogan suffered several serious injuries, including a fractured skull and bleeding to the brain, and was placed in intensive care for eight days after the attack. He regained consciousness and recovered from his injuries but died of cancer last year.
Study identifies major flaws in iBMEC-based models of the blood-brain barrier
A type of cell derived from human stem cells that has been widely used for brain research and drug development may have been leading researchers astray for years, according to a study from scientists at Weill Cornell Medicine and Columbia University Irving Medical Center.
The cell, known as an induced Brain Microvascular Endothelial Cell (iBMEC), was first described by other researchers in 2012, and has been used to model the special lining of capillaries in the brain that is called the blood-brain barrier.
Many brain diseases, including brain cancers as well as degenerative and genetic disorders, could be much more treatable if researchers could get drugs across this barrier. For that and other reasons, iBMEC-based models of the barrier have been embraced as an important standard tool in brain research.
Date Time
Weill Cornell researchers detect key flaw in brain modeling
A type of cell derived from human stem cells that has been widely used for brain research and drug development may have been leading researchers astray for years, according to a study from scientists at Weill Cornell Medicine and Columbia University Irving Medical Center. Lis Lab/Provided
Induced brain microvascular endothelial cells (IBMECs), top, cultured in 3D assume an epithelial organoid structure and express the epithelial cell marker EPCAM (purple). When they are reprogrammed by overexpression of ETV2, ERG and FLI1, they lose EPCAM expression, acquire vascular markers VE-Cad (red) and PECAM1 (green) and are able to fulfill the function of endothelial cells – forming blood vessels, shown in bottom image.
A type of cell derived from human stem cells that has been widely used for brain research and drug development may have been leading researchers astray for years, according to a study from scientists at Weill Cornell Medicine and Columbia University Irving Medical Center.
Thursday, February 4, 2021 - 7:30 am
To the Editor
The family of Larissa and David Redmond would like to thank the entire community for all of their help - financially and with their prayers, cards, food, flowers or just saying how sorry they were.
Special thanks for the fundraisers which made it possible to lay our angel down. Thank you also to the Rescue Team, SLC Sheriff s, Ogdensburg Police Dept., Frary’s Funeral Home, Youmi’s Flowers, the Salvation Army, family & close friends - everyone has been so caring and wonderful to our family.
Also special thanks to Larissa’s second home - the Ogdensburg Boys and Girls Club, her teachers and classmates.