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Infections, cardiopulmonary disease, and second cancers were among the leading causes of nonrelapse deaths in patients receiving CAR T-cell therapy, both in clinical trials and clinical practice.

United statesDana farber cancer instituteLee greenbergerJay spiegelDrug administrationLeukemia lymphoma societyAmerican society of hematologyUniversity of miamiSylvester cancer centerDavid cordasAmerican societyMedscape medical newsLymphoma societyBiologic therapyChimeric antigen receptort cell therapyChimeric antigen receptors