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Colchicine does not reduce primary outcomes in patients undergoing major non-cardiac thoracic surgery: COP-AF trial

Canada: In patients undergoing major non-cardiac thoracic surgery, colchicine fails to significantly reduce perioperative atrial fibrillation (AF) or myocardial injury after non-cardiac surgery.

David conenPopulation health research instituteEuropean society of cardiology congressSociety of cardiologymmatoryHot lineEuropean societyEuropean society of cardiologyAtrial fibrillationMyocardial injuryNon cardiac thoracic surgeryMajor thoracic surgeryCoronary artery disease

No Reduction in AF After Noncardiac Surgery With Colchicine: COP-AF

COP-AF trial results showed no significant reduction in co-primary endpoints of clinically important AF or myocardial injury after noncardiac thoracic surgery, although there were positive trends.

Hong kongNoord hollandFranz weidingerDavid conenAgepha pharmaJean claude tardifChanela foundationHealth canadaHamilton health sciencesEuropean society of cardiologyDivision of cardiology at mcmaster universityDrug administrationMontreal heart instituteCanadian institutes of health researchResearch grants councilClinical trials consortium

Colchicine not protective against AF, myocardial injury after noncardiac chest surgery

Colchicine not protective against AF, myocardial injury after noncardiac chest surgery
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Noord hollandRichard smithDavid conenByscott buzbyEuropean society of cardiology congressMcmaster universityEuropean societyCardiology congressRoche diagnostics

COP-AF: Colchicine Doesn t Cut Perioperative AF or Myocardial Injury Post-Op

(UPDATED) Colchicine wasn’t effective in thoracic surgery, but there were some promising signals worth studying, say investigators.

Noord hollandDavid conenMarc ruelMcmaster university population health research instituteDrug administrationEuropean society of cardiologyMd university of ottawa heart instituteHot lineEuropean societyPopulation health research instituteOttawa heart institute

COP-AF: Colchicine Doesn t Cut Post-Op AF or Myocardial Injury

(UPDATED) Colchicine wasn’t effective in thoracic surgery, but there were some promising signals worth studying, say investigators.

Noord hollandMarc ruelDavid conenMd university of ottawa heart instituteDrug administrationEuropean society of cardiologyMcmaster university population health research instituteHot lineEuropean societyPopulation health research instituteOttawa heart institute