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The two studies are complementary: The study published in Cell looks at the entire human genome and gives a very broad overview of host factors that are required for infection by the virus. The study published in Cell Host and Microbe focuses in detail on a smaller subset of host factors and how they interact. Together, the studies reveal previously unknown potential drug targets for vanquishing the virus. What the Virus Needs From Us Both studies relied on the genome-editing tool CRISPR/Cas9. This versatile tool allows scientists to make precise cuts in the genome. The MSK, Rockefeller, and NYU scientists used CRISPR to systematically knock out genes in human cells and ask whether the loss of that gene’s function impaired the virus’s ability to infect, reproduce in, and ultimately kill the cells.

New yorkUnited statesRockefeller universityYadira soto felicianoDavid allisScott loweCharles riceSloan kettering instituteJohn poirier at new york universityResearch under pressureSloan ketteringJohn poirierNew york universityCell hostVirus needs fromபுதியது யார்க்