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The Medicine Maker Hosts Revealing Discussion with Experts from IPEC-Americas on the Importance of Novel Excipients for Pharmaceuticals

Applying QbD To Incorporate Excipients Into Drug Lifecycle Management

Applying QbD To Incorporate Excipients Into Drug Lifecycle Management
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Integrating Excipients Into QbD For Drug Development Understanding Drift Critical Material Attributes

Integrating Excipients Into QbD For Drug Development Understanding Drift Critical Material Attributes
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Incorporating Excipients Into QbD Studies For Drug Development — An Introduction

Incorporating Excipients Into QbD Studies For Drug Development — An Introduction By Brian Carlin (DFE Pharma), Chris Moreton (FinnBrit Consulting), Dave Schoneker (Black Diamond Consulting), Katherine Ulman (KLU Consulting), Joseph Zeleznik (IMCD) This article is the first in a three-part series based on information from the new guide Incorporation of Pharmaceutical Excipients into Product Development using Quality-by-Design , published by the International Pharmaceutical Excipients Council Federation (IPEC Federation). 1 The International Conference on Harmonization’s (ICH) guidelines related to quality by design (QbD) primarily ICH Q8, as well as Q9, Q10, Q11, and Q12 2-6 are high level and focus on the active pharmaceutical ingredient (API) and finished drug product. Applying API logic to excipients can lead to counterproductive adaptations inconsistent with QbD principles.

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