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Datopotamab Deruxtecan Generates PFS Benefit in Previously Treated HR+/HER2-Low or HER2– Breast Cancer

Datopotamab deruxtecan elicited a statistically significant and clinically meaningful improvement in progression-free survival compared with chemotherapy in patients with inoperable or metastatic hormone receptor–positive, HER2-low or HER2-negative breast cancer.

Daiichi sankyoSusan galbraithKen takeshitaOncology researchDatopotamab deruxtecanPatients with inoperable or metastatic hormone receptor positiveEr2 low or her2 negative breast cancerTropion breast01 trial

ADCs Show Early Promise in NSCLC

Antibody-drug conjugates link a tumor-targeted antibody to a cytotoxic drug through a chemical linker and hold the promise of high potency.

Helena linardouDaiichi sankyoSacituzumab govitecanDatopotamab deruxtecanClinical trials center at metropolitan hospitalDrug administrationWorld conferenceLung cancerComprehensive clinical trials centerMetropolitan hospitalNon small cell lung cancerUng carcinomaAncer lungAlignant neoplasiaBiologic therapySmall cell lung cancer

Datopotamab Deruxtecan Plus Durvalumab Showed Promising Clinical Activity in the First-Line Advanced Non-Small Cell Lung Cancer Setting in TROPION-Lung04 Phase 1b Trial

Datopotamab Deruxtecan Plus Durvalumab Showed Promising Clinical Activity in the First-Line Advanced Non-Small Cell Lung Cancer Setting in TROPION-Lung04 Phase 1b Trial
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Siteman cancer centerUnited statesWashington universityMark rutsteinDaiichi sankyoJennifer brennanAnn oncSaiama waqarCristian massacesiKoji ogiwaraSapporo medical universityWashington university school of medicineInternational agency for research on cancerDaiichi sankyo incOncology clinical developmentWorld health organization

Daiichi Sankyo: Datopotamab Deruxtecan Plus Durvalumab Showed Promising Clinical Activity in the First-Line Advanced Non-Small Cell Lung Cancer Setting in TROPION-Lung04 Phase 1b Trial

Daiichi Sankyo: Datopotamab Deruxtecan Plus Durvalumab Showed Promising Clinical Activity in the First-Line Advanced Non-Small Cell Lung Cancer Setting in TROPION-Lung04 Phase 1b Trial
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Siteman cancer centerUnited statesWashington universityBaden wübergMark rutsteinJennifer brennanDaiichi sankyoSaiama waqarAnn oncCristian massacesiKoji ogiwaraInternational agency for research on cancerWorld health organizationWashington university school of medicineOncology clinical developmentAmerican cancer society

AstraZeneca Data at WCLC Advance Ambition to Have an AstraZeneca Medicine for More Than Half of All Patients Treated for Lung Cancer by 2030

AstraZeneca Data at WCLC Advance Ambition to Have an AstraZeneca Medicine for More Than Half of All Patients Treated for Lung Cancer by 2030
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United kingdomBrendan mcevoyDaiichi sankyoSusan galbraithDave fredricksonNeoadjuvant durvalumabChelsea fordTrastuzumab deruxtecanA health systems approach toLung cancer policy networkLung ambition allianceBroad panelDaiichi sankyo incBreakthrough therapy designationInternational associationLung cancer